Cerebrovascular disease in Brazil from 1990 to 2015: Global Burden of Disease 2015.

Objective: To verify the time trends of mortality rates, years of lost life (YLL), and years lived with disability (YLD) caused by cerebrovascular disease in Brazil between 1990 and 2015. Methods: The estimates from the Global Burden of Diseases 2015 were used to analyze the magnitude and trends of mortality rates and disability-adjusted life years (DALY) for cerebrovascular disease (ICD-10: I-60-69) in the 27 units of the Federation between 1990 and 2015. The states were analyzed by the social development index (SDI), based on average income per person, educational attainment at 15 years- old and total fertility rate. Results: Despite the increase in the absolute number of deaths due to cerebrovascular disease, the proportion of deaths below 70 years of age has been halved between 1990 and 2015. The acceleration of the reduction was higher among women; and increased from 1990 to 2005, when compared to the period from 2005 to 2015. The risk of death has been halved across the country, but states in the lower SDI tertile had less significant reductions (-1.23 and -1.84% a year) compared to the middle tertile (-1.94 and - 2.22%) and the upper tertile (-2.85 and -2.82%) for men and women, respectively. The years lived with disability also presented a reduction among states, but less expressively. Conclusion: Despite the reduction of age-adjusted mortality rates throughout the country, cerebrovascular disease still presents a high disease burden, especially in states with lower socioeconomic development.